This list contains the top 20 most valuable sets based on current market prices or sale prices. It includes both retired sets and sets that are still for sale.
| # | NAME OF THE SET | SET NUMBER | YEAR | |||
|---|---|---|---|---|---|---|
| 1 | Daily Bugle | LEGO 76178 | 2021 | |||
| 2 | Sanctum Sanctorum | LEGO 76218 | 2022 | |||
| 3 | The Milano Spaceship Rescue | LEGO 76021 | 2014 | |||
| 4 | Captain America's Shield | LEGO 76262 | 2023 | |||
| 5 | Hulk vs. Red Hulk | LEGO 76078 | 2017 | |||
| 6 | Sanctum Sanctorum Showdown | LEGO 76108 | 2018 | |||
| 7 | The Hulkbuster Ultron Edition | LEGO 76105 | 2018 | |||
| 8 | Super Hero Airport Battle | LEGO 76051 | 2016 | |||
| 9 | The Guardians' Ship | LEGO 76193 | 2021 | |||
| 10 | Thor's Hammer | LEGO 76209 | 2022 | |||
| 11 | Avengers Helicarrier | LEGO 76153 | 2020 | |||
| 12 | The Milano | LEGO 76286 | 2024 | |||
| 13 | Attack on Avengers Tower | LEGO 76038 | 2015 | |||
| 14 | The Milano vs. The Abilisk | LEGO 76081 | 2017 | |||
| 15 | The Avengers Quinjet City Chase | LEGO 76032 | 2015 | |||
| 16 | Avenjet Space Mission | LEGO 76049 | 2016 | |||
| 17 | Daily Bugle Showdown | LEGO 76005 | 2013 | |||
| 18 | Avengers Tower Battle | LEGO 76166 | 2020 | |||
| 19 | Venomosaurus Ambush | LEGO 76151 | 2020 | |||
| 20 | Thor vs. Hulk Arena Clash | LEGO 76088 | 2017 |
